MDA-MB-415細胞源于一名38歲患有乳腺腺癌女性的胸腔積液,MDA-MB-415細胞表達WNT7B癌基因。MDA-MB-415細胞形成平展延伸的上皮細胞樣,在電鏡下呈現結節,伴隨著延伸的微管和微板。MDA-MB-415細胞不容易用胰酶消化。
Established from the peripheral blood of a 17-year-old woman with acute lymphoblastic leukemia (ALL-L2) in 1990; contains the t(17;19)(q22;p13) TCF3-HLF (E2A-HLF) fusion gene
Established from the lymph node metastasis of a 63-year-old woman with anaplastic papillary thyroid carinoma; cells were described in the literature to not produce hormones, but to be partly positive
SUM159PT (人乳腺癌細胞系) (STR鑒定正確)
EB-3細胞源自一名3歲患有Burkitt's淋巴瘤的黑人男孩的B淋巴細胞,EBNA陽性。
人的cDNA中編碼GADD45的開放閱讀框克隆到表達載體pCMV.3中,轉染結腸癌細胞RKO,建立了RKO-AS45-1細胞株。RKO-AS45-1細胞含有穩定整合巨細胞病毒(CMV)啟動子的表達載體,RKO-AS45-1細胞系和它的母系RKO一起可用于GADD45對DNA修復、凋亡和藥物敏感性研究。